Rajiv K Saxena
Professor Emeritus
Faculty of Life Sciences and Biotechnology (FLSB)

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ACADEMIC APPOINTMENTS:
Professor, FLSB, SAU, 2011 to date
Vice President, South Asian University, New Delhi (2010 to 2016)
Professor and Dean: FLSB, South Asian University, New Delhi (2010 to 2016)
Rector (Pro Vice-Chancellor): Jawaharlal Nehru University, New Delhi (2002-2005)
Dean: SLS, Jawaharlal Nehru University, New Delhi (From 2001-2002)
Professor of Immunology: SLS, Jawaharlal Nehru University, New Delhi (1991-2010)
Officer on Special Duty: South Asian University, New Delhi (2008-2010)
Visiting Professor: University of Pittsburgh School of Medicine, PA, USA (1990-1992); NIOSH, CDC, WV, USA (1999-2001); US-EPA, Durham, North Carolina, USA (2005-2007).
Post Doctoral Fellow: NIA, NIH, USA (1978-1984)

Qualifications

  • PhD in Biochemistry from All India Institute of Medical Sciences, New Delhi , in 1977
  • M.Sc. in Biochemistry from All India Institute of Medical Sciences, New Delhi , in 1973

Awards & Honours

  • Prof. TR Sheshadri Award by Delhi University at Delhi, in 1970
  • NII Senior Scientist Oration and Gold Medel
  • Fellowship, National Academy of Science
  • Fellowship, Indian Academy of Science
  • Fellowship, Indian National Science Academy
  • JC Bose National Research Fellowship

Recent Publications

  • Alam, A., Puri, N. and Saxena, R.K. (2016) Uptake of poly-dispersed single-walled carbon nanotubes and decline of functions in mouse NK cells undergoing activation,J.Immunotoxicology, DOI: 10.1080/1547691X.2016.1191562

  • Chaterjee, S. and Saxena, R.K. (2016) Identification of stages of erythroid differentiation in bone marrow and erythrocyte subpopulations in blood circulation that are preferentially lost in autoimmune hemolytic anemia in mouse PLoS One 11(11): e0166878. doi:10.1371/journal.pone.0166878

  • Chaterjee, S. and Saxena, R.K. (2015) Preferential elimination of older erythrocytes in circulation and depressed bone marrow erythropoietic activity contribute to cadmium induced anemia in mice.  PLoS One 10 (7): e0132697. doi:10.1371/ journal. pone.0132697

  • Kumari, M. and Saxena, R.K. (2015) Proliferative activity and changes in the relative  proportion of T1 and TII populations in cultured primary  epithelial cells, isolated from mouse lung. Cell Biology: Research and Therapy 4:3. doi:10.4172/2324-9293.1000121

  • Bhardwaj N. and Saxena R. K. (2015)  Selective loss of younger erythrocytes from blood circulation and changes in erythropoietic patterns in bone marrow and spleen in mouse anemia induced by poly-dispersed single wall carbon nanotubes. Nanotoxicology 9(8):1032-40.

  • Bhardwaj N. and Saxena R. K. (2014) Elimination of young erythrocytes from blood circulation and altered erythropoietic patterns during paraquat induced anemic phase in mice. PLoS ONE  9(6): e99364

  • Abbas, Z., Puri, N. and Saxena, R.K. (2014) Lipid antigen presentation through CD1d pathway in mouse lung epithelial cells, macrophages and dendritic cells and its suppression by poly-dispersed single-walled carbon nanotubes. Toxicology in vitro 29(6):1275-82

  • Bhardwaj N. and Saxena R. K. (2013)  Heterogeneity of reticulocyte population in mouse peripheral blood. Current Science 105, 1611-1614.

  • Alam, A., Sachar, S., Puri, N. and Saxena, R.K. (2013). Interactions of poly-dispersed single walled Carbon Nanotubes with T cells resulting in down regulation of allogeneic CTL responses in vitro and in vivo. Nanotoxicology 7, 1351-1360 [Included as a Key Nanotechnology Articles on Global Medical Discovery web-portal (globalmedicaldiscovery.com]

  • Saxena, R.K., Bhardwaj, N, Sachar, S, Puri, N. and Khandelwal, S (2012) A double in vivo biotinylation  (DIB) technique for objective assessment of aging and clearance of mouse erythrocytes in blood circulation, Transfusion Medicine and Hemotherapy 39, 335-341

  • Kumari, M., Sachar, S. and Saxena, R.K. (2012) Loss of proliferative and antigen presentation activity following internalization of poly-dispersed single-walled carbon nanotubes by primary lung epithelial cells PLOS one 7 (2): e31890

  • Sachar, S and Saxena R.K. (2011). Cytotoxic effect of poly-dispersed single walled carbon nano-tubes on erythrocytes. PLOS one 6 (7): e22032

  • Kumari, M. and Saxena, R.K. (2011) . Relative efficacy of uptake and presentation of BCG antigens by type I mouse lung epithelial cells and peritoneal macrophages . Infection and Immunity  79:3159-67

  • Saxena, R.K., McClure, M, Hays, M., Green, F.H.Y., McPhee, L.J., Vallyathan, V. and Gilmour, M.I. (2010) . Quantitative assessment of elemental carbon in the lungs of never smokers, cigarette smokers and coal miners . J. Toxicol. Environ. Health . 74: 706-715.

  • Saxena, R.K., Gilmour, M.I., Schladweiler, M.C., McClure, M., Hays, M. and Kodavanti, U.P. (2009). Differential Pulmonary Retention of Diesel Exhaust Particles in Wistar Kyoto and Spontaneously Hypertensive Rats . Toxicological Sci. 111:392-401.

  • Saxena, R.K., Gilmour, M.I. and Hays, M.D. (2008) Isolation and quantitative estimation of diesel exhaust and carbon black particles ingested by lung epithelial cells and alveolar macrophages in vitro . BioTechniques ,44: 799-805.

  • Saxena, R.K., Williams, W., McGee, J.K., Daniels, M.J., Boykin, E. and Gilmour, M.I. (2007) .Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-wall carbon Nanotubes . Nanotoxicology , 1: 291-300.

Research Interests

  • Natural and adaptive Immune response in lungs
  • Interactions of nanoparticles with living systems
  • Ontogeny of erythrocytes and their turnover in blood

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