Pankaj Kumar Giri
Assistant Professor
Faculty of Life Sciences and Biotechnology (FLSB)
South Asian University,
Room no.229, Akbar Bhawan, Chankya Puri
New Delhi-110021
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Profile

Assistant Professor, South Asian University, New Delhi. INDIA (2019-present)
Postdoctoral Research Scientist, Columbia University, New York,USA.(2015-2019)
Research Associate, The Scripps Research Institute, USA.(2012-2014)
Teaching Assistant, National University of Singapore, Singapore.(2007-2012)

Qualifications

  • Ph.D from National University of Singapore, Singapore , in 2012
  • Master of Science (Biotechnology) from Banaras Hindu University, INDIA , in 2006

Recent Publications

  • Lim, J*.; Giri, P. K.*#; Kazadi, D.; Laffleur, B.; Zhang, W.; Grinstein, V.; Pefanis, E.; Brown, L. M.; Ladewig, E.; Martin, O.; Chen, Y.; Rabadan, R.; Boyer, F.; Rothschild, G.; Cogné, M.; Pinaud, E.; Deng, H.; Basu, U.#, Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. Cell 169 (3), 523-537.e15. . [ *-Co-first authors, #-Corresponding Author]

  • de Vera IMS, Munoz-Tello P, Dharmarajan V, Marciano DP, Matta-Camacho E, Giri PK, Shang J, Hughes TS, Rance M, Griffin PR, Kojetin DJ. (2018) Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1. Structure 2019 Jan 2; 27(1):66-77.e5.

  • de Vera, I.M.S.*, Giri, P.K*., Munoz-Tello, P., Brust, R., Fuhrmann, J., Matta-Camacho, E., Shang, J., Campbell, S., Wilson, H.D., Granados, J., et al. (2016). Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1. ACS Chemical Biology 11, 1795-1799. [ *-Co-first authors]

  • Hughes TS, Giri P.K., de Vera IM, Marciano DP, Kuruvilla DS, Shin Y, Blayo AL, Kamenecka TM, Burris TP, Griffin PR, Kojetin DJ.(2014) An alternate binding site for PPARγ ligands. Nature Communications2014 Apr 7; 5:3571

  • Giri P.K., Song FJ, ShanmugamMK, DingJL, Sethi G, Swaminathan K, Sivaraman J (2012) NMR structure of Carcinoscorpiusrotundicaudathioredoxin related protein 16 and its role in regulating transcription factor NF-κB activity .Journal of Biological Chemistry (JBC) 2012 Aug 24; 287(35): 29417-28

  • Giri P.K., Tang X, Thangamani S, Shenoy RT, Ding JL, Swaminathan K, SivaramanJ (2010) Modifying the substrate specificity of Carcinoscorpius rotundicauda serine protease inhibitor domain 1 to target thrombin. PLoS One 2010,5: e15258

Research Interests

  • My research interests’ lie in the development of single cell epi-transcriptomics combine with next generation sequencing and super/high-resolution microscopy (supplemented with biophysical & biochemical methods) to delineate the role of “Nuclear Receptors and Non-coding RNAs” in hormone-sensitive cancers.

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